Notices. DEPARTMENT OF HEALTH AND HUMAN SERVICES
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/register/2008/02/13/08-603A research copy — for the controlling text, always check the official state or federal source. Not legal advice.
BILLING CODE 4165-16-M DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institutes of Health/National Institute of Environmental Health Sciences; Proposed Collection; Comment Request The Parkinson's, Genes and Environment
(PAGE)Study II *Summary:* In compliance with the requirement of Section 3506(c)(2)(A) of the Paperwork Reduction Act of 1995, for opportunity for public comment on proposed data collection projects, the National Institute of Environmental Health Sciences (NIEHS), the National Institutes of Health
(NIH)will publish periodic summaries of proposed projects to be submitted to the Office of Management and Budget
(OMB)for review and approval. *Proposed Collection: Title:* The Parkinson's, Genes and Environment
(PAGE)Study II. *Type of Information Collection Request:* NEW. *Need and Use of Information Collection:* We propose a large case-control study to evaluate roles of environmental exposures, genes, and gene-environment interactions in the etiology of late-onset sporadic Parkinson's disease (PD). This project, the Parkinson's, Genes and Environment Study II (PAGE II), will be developed based on the infrastructure that was set up for the ongoing PAGE I project. PAGE I was designed to prospectively evaluate diet and lifestyle exposures in relation to PD risk. In PAGE I, we expect to recruit approximately 1,200 incident PD cases and 2,800 controls from the NIH-AARP Diet and Health
(DH)cohort. The dietary and lifestyle data were collected as part of the NIH-AARP DH baseline surveys in the mid-1990s by investigators from the National Institute of Cancer. The cases in PAGE I were PD cases who reported a physician diagnosed PD during the 10 year follow-up of NIH-AARP DH cohort and controls were appropriately selected by frequency matching from participants without PD in the same cohort. As part of PAGE I, we are confirming PD diagnoses for self-identified PD cases by contacting their neurologists and reviewing medical records and are collecting saliva samples for genetic testing from both cases and appropriately selected controls. As the NIH-AARP DH study was designed to examine dietary and lifestyle exposures important in the etiology of cancer, many environmental exposures key to PD research were not collected. Examples include pesticide use, occupational history, history of infections, and use of statins. Therefore the primary aim of the PAGE II project is to retrospectively collect these important environmental exposures from PD cases and appropriately selected controls. Cases and controls identified from PAGE I will be re-contacted and interviewed for data collection in PAGE II. Assuming a 70% response rate from cases and controls, we expect to obtain this information from approximately 850 PD cases and 1960 controls. This data collection, together with the dietary and lifestyle data and genetic samples obtained in PAGE I, will make the PAGE study one of the largest and most comprehensive studies to date to examine environmental and genetic causes of PD. *Frequency of Response:* One 90 minute long telephone interview. *Affected Public:* Individuals. *Type of Respondents:* We will enroll men and women who participated in the PAGE I study. The annual reporting burden is as follows: *Estimated Number of Respondents:* 2810. *Estimated Number of Responses per Respondent:* 1 computer assisted telephone interview (CATI). *Average Burden Hours per Response:* 1.5. *Estimated Total Burden Hours Requested:* 4215. The annualized cost to respondents is estimated at $30 (assuming $20 hourly wage × 1.50 hours) for the interview. There are no Capital Costs to report. There are no Operating or Maintenance Costs to report. *Request for Comments:* Written comments and/or suggestions from the public and affected agencies are invited on one or more of the following points:
(1)Whether the proposed collection of information is necessary for the proper performance of the function of the agency, including whether the information will have practical utility;
(2)The accuracy of the agency's estimate of the burden of the proposed collection of information, including the validity of the methodology and assumptions used;
(3)Ways to enhance the quality, utility, and clarity of the information to be collected; and
(4)Ways to minimize the burden of the collection of information on those who are to respond, including the use of appropriate automated, electronic, mechanical, or other technological collection techniques or other forms of information technology. *For Further Information:* To request more information on the proposed project or to obtain a copy of the data collection plans and instruments, contact: Dr. Honglei Chen, Epidemiology Branch, NIEHS, Building 101, A3-05, P.O. Box 12233, Research Triangle Park, NC 27709 or call non-toll-free number
(919)541-3782 or E-mail your request, including your address to: *chenh2@a_niehs.nih.gov* . *Comments Due Date:* Comments regarding this information collection are best assured of having their full effect if received within 60 days of the date of this publication. Dated: January 22, 2008. Marc S. Hollander, NIEHS, Associate Director for Management. [FR Doc. E8-2606 Filed 2-12-08; 8:45 am] BILLING CODE 4140-01-P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. Appendix 2), notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. *Name of Committee:* Center for Scientific Review Special Emphasis Panel; PAR-07-350: Quality of Eggs and Pre-implantation Embryos. *Date:* February 19, 2008. *Time:* 1 p.m. to 2 p.m. *Agenda:* To review and evaluate grant applications. *Place:* Bethesda Marriott, 5151 Pooks Hill Road, Bethesda, MD 20814. *Contact Person:* Syed M. Amir, Phd, Scientific Review Administrator, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 6172, MSC 7892, Bethesda, MD 20892, 301-435-1043, *amirs@csr.nih.gov.* This notice is being published less than 15 days prior to the meeting due to the timing limitations imposed by the review and funding cycle. *Name of Committee:* Center for Scientific Review Special Emphasis Panel; Global Infectious Disease Training Program. *Date:* February 20, 2008. *Time:* 8 a.m. to 5 p.m. *Agenda:* To review and evaluate grant applications. *Place:* The River Inn, 924 25th Street, NW., Washington, DC 20037. *Contact Person:* Dan D. Gerendasy, Phd, Scientific Review Administrator, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 5132, MSC 7843, Bethesda, MD 20892, 301-594-6830, *gerendad@csr.nih.gov.* This notice is being published less than 15 days prior to the meeting due to the timing limitations imposed by the review and funding cycle. *Name of Committee:* Center for Scientific Review Special Emphasis Panel; International Research in Infectious Diseases. *Date:* February 21, 2008. *Time:* 8 a.m. to 5 p.m. *Agenda:* To review and evaluate grant applications. *Place:* The River Inn, 924 25th Street, NW., Washington, DC 20037. *Contact Person:* Dan D. Gerendasy, Phd, Scientific Review Administrator, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 5132, MSC 7843, Bethesda, MD 20892, 301-594-6830, *gerendad@csr.nih.gov.* This notice is being published less than 15 days prior to the meeting due to the timing limitations imposed by the review and funding cycle. *Name of Committee:* Center for Scientific Review Special Emphasis Panel; Sleep and Courtship Behavior. *Date:* February 25, 2008. *Time:* 11 a.m. to 1 p.m. *Agenda:* To review and evaluate grant applications. *Place:* National Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892 (Telephone Conference Call). *Contact Person:* Lawrence Baizer, PhD, Scientific Review Administrator, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 4152, MSC 7580, Bethesda, MD 20892
(301)435-1257, *baizerl@csr.nih.gov* . This notice is being published less than 15 days prior to the meeting due to the timing limitations imposed by the review and funding cycle. *Name of Committee:* Center for Scientific Review Special Emphasis Panel; Member Conflicts: Circadian Rhythms and Sleep Apnea. *Date:* February 27, 2008. *Time:* 1 p.m. to 3 p.m. *Agenda:* To review and evaluate grant applications. *Place:* National Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892, (Telephone Conference Call). *Contact Person:* Christine L. Melchior, PhD, Scientific Review Administrator, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 5176, MSC 7844, Bethesda, MD 20892, 301-435-1713, *melchioc@csr.nih.gov* . *Name of Committee:* Center for Scientific Review Special Emphasis Panel; Fellowships in Cognition, Language and Perception—Special Emphasis Panel. *Date:* March 3, 2008. *Time:* 5 p.m. to 6 p.m. *Agenda:* To review and evaluate grant applications. *Place:* Fairmont Hotel, 2401 M Street, NW., Washington, DC 20037. *Contact Person:* Dana Jeffrey Plude, PhD, Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 3176, MSC 7848, Bethesda, MD 20892, 301-435-2309, *pluded@csr.nih.gov* . *Name of Committee:* Center for Scientific Review Special Emphasis Panel; Molecuar Tumorigenesis. *Date:* March 13, 2008. *Time:* 2:30 p.m. to 3:30 p.m. *Agenda:* To review and evaluate grant applications. *Place:* National Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892, (Telephone Conference Call). *Contact Person:* Syed M. Quadri, PhD, Scientific Review Administrator, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 6210, MSC 7804, Bethesda, MD 20892, 301-435-1211, *quadris@csr.nih.gov* . *Name of Committee:* Center for Scientific Review Special Emphasis Panel; Genetics of Complex Psychiatric Disorders. *Date:* March 21, 2008. *Time:* 1 p.m. to 3 p.m. *Agenda:* To review and evaluate grant applications. *Place:* National Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892, (Telephone Conference Call). *Contact Person:* Barbara J. Thomas, PhD, Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 2218, MSC 7890, Bethesda, MD 20892, 301-435-0603, *bthomas@csr.nih.gov.* *Name of Committee:* Center for Scientific Review Special Emphasis Panel; Fellowships: Physiology and Pathobiology of Organ Systems. *Date:* March 25, 2008. *Time:* 8 a.m. to 6 p.m. *Agenda:* To review and evaluate grant applications. *Place:* Hyatt Regency Bethesda, One Bethesda Metro Center, 7400 Wisconsin Avenue, Bethesda, MD 20814. *Contact Person:* Abdelouahab Aitouche, PhD, Scientific Review Administrator, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 2183, MSC 7818, Bethesda, MD 20892, 301-435-2365, *abdelouahaba@csr.nih.gov.* *Name of Committee:* Center for Scientific Review Special Emphasis Panel; Cell Biology SBIR/STTR Applications. *Date:* March 25-26, 2008. *Time:* 9 a.m. to 5 p.m. *Agenda:* To review and evaluate grant applications. *Place:* National Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892, (Virtual Meeting). *Contact Person:* David Balasundaram, PhD, Scientific Review Administrator, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 5189, MSC 7840, Bethesda, MD 20892, 301-435-1022, *balasundaramd@csr.nih.gov.* *Name of Committee:* Center for Scientific Review Special Emphasis Panel; Small Business Applications in Development and Aging. *Date:* March 26, 2008. *Time:* 1 p.m. to 4 p.m. *Agenda:* To review and evaluate grant applications. *Place:* National Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892, (Telephone Conference Call). *Contact Person:* Cathy Wedeen, PhD, Scientific Review Administrator, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 3213, MSC 7808, Bethesda, MD 20892, 301-435-1191, *wedeenc@csr.nih.gov.* *Name of Committee:* Center for Scientific Review Special Emphasis Panel; Crystallography Research Resource—Program Project. *Date:* March 26-28, 2008. *Time:* 6 p.m. to 12 p.m. *Agenda:* To review and evaluate grant applications. *Place:* Hotel Lombardy, 2019 Pennsylvania Avenue, NW., Washington, DC 20006. *Contact Person:* Nuria E. Assa-Munt, PhD, Scientific Review Administrator, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 4164, MSC 7806, Bethesda, MD 20892,
(301)451-1323, *assamunu@csr.nih.gov.* *Name of Committee:* Center for Scientific Review Special Emphasis Panel; Circulation Regulation and Pathophysiology. *Date:* March 27-28, 2008. *Time:* 8 a.m. to 8 p.m. *Agenda:* To review and evaluate grant applications. *Place:* National Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892, (Virtual Meeting). *Contact Person:* Ai-Ping Zou, PhD, MD, Scientific Review Administrator, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 4118, MSC 7814, Bethesda, MD 20892,
(301)435-1777, *zouai@csr.nih.gov.* *Name of Committee:* Center for Scientific Review Special Emphasis Panel; FIRCA and GRIP in Behavioral and Social Sciences. *Date:* March 31, 2008. *Time:* 8 a.m. to 6 p.m. *Agenda:* To review and evaluate grant applications. *Place:* Georgetown Suites, 1000 29th Street, NW., Washington, DC 20007. *Contact Person:* Manana Sukhareva, PhD, Scientific Review Administrator, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 3214, MSC 7808, Bethesda, MD 20892,
(301)435-1116, *sukharem@csr.nih.gov.* Catalogue of Federal Domestic Assistance Program Nos. 93.306, Comparative Medicine; 93.333, Clinical Research, 93.306, 93.333, 93.337, 03.393-93.396, 93.837-93.844, 93.846-93.878, 93.892, 93.893, National Institutes of Health, HHS) Dated: February 5, 2008. Jennifer Spaeth, Director, Office of Federal Advisory Committee Policy. [FR Doc. 08-603 Filed 2-12-08; 8:45 am]