Notices. DEPARTMENT OF HEALTH AND HUMAN SERVICES
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/register/2003/02/07/03-3024A research copy — for the controlling text, always check the official state or federal source. Not legal advice.
BILLING CODE 4163-18-P DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30DAY-27-03] Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and Prevention
(CDC)publishes a list of information collection requests under review by the Office of Management and Budget
(OMB)in compliance with the Paperwork Reduction Act (44 U.S.C. Chapter 35). To request a copy of these requests, call the CDC Reports Clearance Officer at
(404)498-1210. Send written comments to CDC, Desk Officer, Human Resources and Housing Branch, New Executive Office Building, Room 10235, Washington, DC 20503. Written comments should be received within 30 days of this notice. *Proposed Project:* Exposure to Aerosolized Brevetoxins During Red Tide Events (OMB No. 0920-0494)—Extension—National Center for Environmental Health (NCEH), Centers for Disease Control and Prevention (CDC). *Gymnodinium breve* is the marine dinoflagellate responsible for extensive blooms (called “red tides”) that form in the Gulf of Mexico. *G. breve* produces potent toxins, called brevetoxins, that have been responsible for killing millions of fish and other marine organisms. The biochemical activity of brevetoxins is not completely understood and there is very little information regarding human health effects from environmental exposures, such as inhaling brevetoxin that has been aerosolized and swept onto the coast by offshore winds. CDC, National Center for Environmental Health is planning to recruit 100 people who work along the coast of Florida and who potentially will be occupationally exposed to aerosolized red tide toxins some time during the year following recruitment. We plan to administer a base-line respiratory health questionnaire and conduct pre- and post-shift pulmonary function tests during a time when there is no red tide reported near the area. When a red tide develops, we plan to administer a symptom survey and conduct pulmonary function testing
(PFT)on a group of study participants who are working in the area where the red tide is near shore and on a control group of study participants who are not working in an area where the red tide is near shore ( *i.e.* , are not exposed to the red tide). We will then compare
(1)symptom reports before and during the red tide and
(2)the changes in baseline PFT values during the work shift (differences between pre- and post-shift PFT results without exposure to red tide) with the changes in PFT values during the work shift when individuals are exposed to red tide. In addition, we plan to assist in collecting biological specimens (inflammatory cells from nose and throat swabs) to assess whether they can be used to verify exposure and to demonstrate a biological effect ( *i.e.* , inflammatory response) from exposure to red tide. We have collected part of the data, but, because we are dealing with natural phenomena and are subject literally to the tides, we must extend our data collection time for an additional two years. The estimated annualized burden is 206 hours. Respondents Number of respondents Number of responses per respondent Average burden per response (in hours) Pulmonary History Questionnaire 20 1 20/60 Spirometry 20 20 20/60 Nasal and Throat Swabs 20 20 5/60 Symptom Questionnaire 20 20 5/60 Dated: January 31, 2003. Thomas Bartenfeld, Acting Associate Director for Policy, Planning and Evaluation, Centers for Disease Control and Prevention. [FR Doc. 03-3024 Filed 2-6-03; 8:45 am]