Sec. 3. Schedule I classification of nitazenes
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Schedule I of section 202(c) of the Controlled Substances Act ( 21 U.S.C. 812(c) ) is amended by adding at the end the following: Unless specifically exempted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of a 2-benzylbenzimidazole opioid, or which contains the salts, isomers, and salts of isomers of a 2-benzylbenzimidazole opioid. For purposes of paragraph (1), the term 2-benzylbenzimidazole opioid includes the following:
A substance that is structurally related to 2-benzylbenzimidazole with the following modifications: At the 1-position, substitution with an alkyl linker connected to a substituted amine group containing hydrogen, alkyl, alkenyl, or heteroaryl group, such as a morphilino, pyrrolidino, or piperidinyl groups, whether or not further substituted. At the 2-position— replacement of the alkyl portion of the benzyl group with a substituted or unsubstituted alkyl, alkoxy, carbamates group, nitrogen, sulfur, or oxygen atom; or replacement of the phenyl portion of the benzyl group with an aryl or heteroaryl group.
Substitution on the phenyl portion of the benzimidazole ring with a hydrogen atom, halogen, nitro, cyano, substituted or unsubstituted amide, amine, alkyl, alkoxy, aryl, or heteroaryl group. At the 6-position, substitution with hydrogen, nitro, trifluoromethyl, methoxy, trifluoromethoxy, cyano, and halogen groups. A substance that exhibits agonist activity at the mu-opioid receptor. Etonitazene, clonitazene, metonitazene, isotonitazene, protonitazene, butonitazene, etodesnitazene, flunitazene, N-pyrrolidino etonitazene, N-desethyl isotonitazene, and N-piperidinyl etonitazene. .
Any substance included in the amendment made by subsection
(a)that was temporarily scheduled under section 201(h) of the Controlled Substances Act ( 21 U.S.C. 811(h) ) shall be deemed permanently scheduled and subject to the requirements of schedule I of section 202(c) of that Act ( 21 U.S.C. 812(c) ) as of the date of enactment of this Act. Nothing in this subsection shall be construed to authorize the initiation of new research using 2-benzylbenzimidazole opioids, as defined in subsection
(f)of schedule I of section 202(c) of the Controlled Substances Act ( 21 U.S.C. 812(c) ), as added by subsection
(a)of this section, without proper registration and scheduling compliance.
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